Phage/Host Combat: Phage Strategies for Taking Over the Host and Host Strategies for Defense
Guest Editors
Deborah M. Hinton, PhD
Chief, Gene Expression and Regulation Section,
Laboratory of Biochemistry and Genetics,
National Institute of Diabetes and Digestive and Kidney Diseases,
National Institutes of Health,
Bethesda, MD
Paul E. Turner, PhD
Rachel Carson Professor of Ecology & Evolutionary Biology,
Director of Center for Phage Biology and Therapy,
Director of Quantitative Biology Institute and Program in Physics, Engineering & Biology,
Yale University,
Microbiology Faculty,
Yale School of Medicine,
New Haven, CT
As coined by Graham Hatfull, the ‘dark matter’ of the biosphere constitutes a vast majority of phage genes, which have no homologs within prokaryotic or eukaryotic genomes. Recent work has shown that many of these genes encode functions that work in host takeover and/or optimization of the phage infection. Understanding the molecular mechanisms of these phage genes may provide insights into new ways to generate anti-bacterial strategies, information that is crucial in light of the global crisis of growing antibiotic resistance. This Special Issue will focus on the identification, characterization, and mechanisms of phage genes involved in phage/host interactions, applications that use such genes to disrupt host functions, and host responses to these phage strategies.
Papers reporting new data, reviews, or hybrids of both are welcome. Please submit your article for the Special Issue by July 1, 2022.
PHAGE: Therapy, Applications, and Research is the only peer-reviewed journal dedicated to fundamental bacteriophage research and its applications in medicine, agriculture, aquaculture, veterinary applications, animal production, food safety, and food production. Under the distinct leadership of Editor-in-Chief Martha Clokie, PhD, University of Leicester, United Kingdom, the Journal showcases groundbreaking research, reviews, commentaries, opinion pieces, profiles, and perspectives dedicated to defining the roles of phages in all facets of microbiology and microbial ecology and exploring their potential to manipulate bacterial communities and treat infection.
PHAGE is the critical resource for molecular biologists, microbiologists, bacteriologists, bioengineers, immunologists, clinicians, and translational biologists, and aims to unify this evolving cluster of innovative researchers, industry leaders, clinicians, and policy makers. The Journal also advances knowledge and development in this re-emerging area of research and opens doors for new ideas and funding opportunities for researchers and clinicians in the field.
To begin your submission, log into PHAGE 's Manuscript Submission Site, and please include in your cover letter that you are submitting for the special issue.
Visit the Journal's website to view more information for authors including manuscript guidelines, information on available author services, and publication costs.
Contact the Editorial Office with any questions you may have.