About This Book

The essential book series highlighting the seminal work and important advances in specific areas of tissue engineering development

All of the tissues in our bodies derive from the fusion of genetic material that occurs when a sperm fertilizes an egg. The first several divisions contain the ‘inner cell mass,’ which are harvested to be grown as embryonic stem cells (ESC) in culture. ESC’s have the ability to differentiate into any tissue of their organism of origin. While much remains to be learned about stem cells, development pathways, and control methods, many key foundation steps are now in place. The next phase of stem cell development will likely revolve around an increased understanding of molecular mechanisms underlying differentiation.

Advances in Tissue Engineering, Volume 2: Stem Cells presents the latest findings and research on:


• The interplay of stem cells in developing parenchymal tissues and their vasculature
• Micro environmental influences that affect stem cell development
• Molecular mechanisms underlying stem cell differentiation
• Major influences that are being applied to stem cells to guide their development, 
   including cellular influences, physical factors, and soluble agents
• Target enhancement technologies for optimal localization of mesenchymal stem
   cells in the body
• Technical issues including cellular characterization and manufacturing scale-up

“The Advances in Tissue Engineering book series is an important new tool to students, scientists, and engineers interested in the field of tissue engineering and regenerative medicine. It identifies the important issues of the field and provides the reader with state of the art knowledge which can then be applied to new solutions.”
       Joseph. P. Vacanti, MD
       Harvard Stem Cell Institute
       Massachusetts General Hospital

“Vascular growth and stem cells undoubtedly play a central role in normal tissue development and growth. The grand challenge is to figure out how to transform the ever-expanding knowledge of key biomolecular signals that regulate tissue morphogenesis into therapies that promote functional tissue regeneration. The Advances in Tissue Engineering book series begins with a state-of-the-art collection of the latest scientific advances in therapeutic angiogenesis and stem cell delivery strategies that will be needed to enable development of the next generation of tissue regenerative technologies.”
       Robert Guldberg, PhD
       Georgia Institute of Technology
       The George W. Woodruff School of Mechanical Engineering

 You may also be interested in Advances in Tissue Engineering, Volume 1: Angiogenesis

The views, opinions, findings, conclusions and recommendations set forth in any Journal article are solely those of the authors of those articles and do not necessarily reflect the views, policy or position of the Journal, its Publisher, its editorial staff or any affiliated Societies and should not be attributed to any of them.