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PREPARATION OF MANUSCRIPTS - TABLES AND ILLUSTRATIONS - PROTOCOL TABLE - FIGURE LAYOUT - CONCENTRATION RESPONSE PLOTS - BAR GRAPHS - ERROR BARS AND DEFINITION -  Z' FACTOR - CHEMICAL STRUCTURES - COVER SUBMISSIONS - Animal and Human Tissue Guidelines - COMPARATIVE STUDIES - REFERENCES - PERMISSIONS - AUTHORSHIP - page proofs - REPRINTS

 

ASSAY and Drug Development Technologies focuses on early-stage screening techniques and tools that optimize the identification of novel leads and targets for new drug development, running the spectrum from nanotechnology through cellular imaging. Case studies are presented, and technology applications are extensive. Articles published in ASSAY emphasize methodologies and technologies to accelerate drug discovery.

Included topics are: State-of-the-art research, methods, materials, and protocols in assay design and target development; High throughput screening; High throughput chemistry; Lab automation; Data analysis and information management; Microplate standards; Screen design and advanced technology; Protein structure and function; Compound library generation; Bioinformatics and data mining; Validation strategies; Biosensors; Detection technologies; Miniaturization and nanotechnology; Protein–protein interaction as novel drug targets; Novel screening methods with high information content; Metabolically engineered cells and organisms; Imaging technologies for live cells, tissues, and small animals; and Virtual screening.

Manuscripts submitted to this Journal must not be under consideration elsewhere.

Submitting Your Manuscript

ASSAY and Drug Development Technologies welcomes format-neutral manuscripts for first-time submissions. Newly submitted manuscripts will not be un-submitted for formatting issues.  However, after the initial peer review process, revised submissions must follow correct journal formatting and file guidelines, as described in the Instructions for Authors.

ORCID IDs

All submitting authors are required to complete their submissions using an ORCID identifier. Please visit the ORCID website for more information, or to register.

All manuscripts must be submitted online using the following URL:
http://mc.manuscriptcentral.com/assay

Authors must include a letter of transmittal that includes the paper’s title, corresponding author’s name, address, institutional affiliation(s), a telephone and fax number, (including the country and city code if outside the U.S.), and Email address. The cover letter should indicate that the work has not previously been published, is not under consideration for publication elsewhere, that all authors have read and agree with the contents of the submission, and that all authors have contributed substantially to the work.

 

Keywords (Areas of Expertise)

 

To facilitate the peer review process, select 4-6 keywords from the drop-down list of pre-selected terms when submitting your manuscript.   These keywords will assist in the selection of skilled reviewers in the field for the purposes of peer review.

English Grammar and Style Refinement: The Editors’ goal is for ASSAY and Drug Development Technologies to provide a global forum that promotes discourse among drug discovery researchers worldwide. Thus submission of articles by authors from non-English speaking countries is strongly encouraged. Authors whose native language is not English are advised to use an editing service to refine the manuscript before submission to ASSAY. Peer reviewers will then be able to evaluate the scientific content and organization of a paper without becoming distracted by grammatical details. Our aim is to avoid the obscuring of excellent science by a difficult to read manuscript.

Expert editors at Mary Ann Liebert, Inc. are available to refine your manuscript for word usage, grammar, sentence construction, and formatting prior to submission for peer review. Please note that use of this editing service does not guarantee acceptance by the Journal. After editing the paper it will go through the usual full peer review process. Even if the paper is not accepted by the journal, it will have been substantially improved and may then be submitted for publication in another Journal. For further information and costs, please e-mail Georgia Prince at the publisher’s office: EditingServices@liebertpub.com. Please be sure to include the name of the journal and whether or not the paper has been officially submitted to the journal. Alternatively, authors may select from one of the numerous scientific editing services that may be found through a web-based search.

PREPARATION OF MANUSCRIPTS

 

All text files must be submitted in Word.   Do not upload PDFs.  Submissions of manuscripts must be double-spaced. Please do not embed artwork or tables within the text document. Figures should be supplied in separate, individual files, be labeled clearly, and should be in TIFF or EPS formats.  Tables should be supplied in a separate Word document, not in PDF format.  Please see the Tables and Illustrations section for further details on art submission.

 

IMPORTANT:

Please upload individual files of all manuscript material – do NOT upload a single PDF file containing all text, figure, and table files of your paper. Once all individual files are uploaded on to Manuscript Central, the system will automatically create a single PDF proof for you and for the peer-review process.

Please follow this sequence of sections:

               Number each page of text consecutively. Number all figures and tables.

               Title page must contain: (1) the complete title of the paper; (2) the full names (including first names), full mailing addresses, full contact information (telephone, fax, and e-mail address), and affiliations of each author; (3) a brief running title; (4) the corresponding author’s complete contact information including full mailing and e-mail addresses. 

•             Manuscript keywords (search terms): On the title page of the manuscript, include a minimum of three (3), maximum of six (6), search terms that will aid in the discoverability of the article in indexing services and search engines.  These terms may or may not be different from the terms you selected for the peer review process and areas of expertise.  You will be asked to retype these search terms in the submission form when uploading your manuscript.  These keywords will be included in the published article.  If the search terms entered do not match the manuscript, the manuscript will serve as the default.

 

               Title: Please do not use “Novel” or “New” in the article title.

               Abstract: 250 words or less, without the use of subheadings. References are not permitted in the abstract.

               Abbreviations: Please include a list of all abbreviations used in the article. All acronyms and their definitions should be spelled out in a separate list on a separate page immediately after the title page.

               Introduction: Summarize the background of the technology and its significance and novelty. Results should NOT be included in the introduction.

               Materials and Methods: ASSAY is method-oriented. Sources of specific materials, including reagents, software, and instrumentation, should be specified, marked with ™ or ® if they are trademarked or registered. These marks need only be cited at the product’s first mention in the abstract, and then once again in text. Use only acronyms in text. When using specific brand names of drugs or devices, please include the manufacturer’s name and location (including city and state) in parentheses.

               Results.

               Discussion: The results and discussion sections of short articles may be combined for more effective presentation.

               Acknowledgments.

               AUTHOR DISCLOSURE STATEMENT: All authors are expected to disclose any institutional or commercial affiliations that might pose a conflict of interest regarding the publication of a manuscript. Institutional affiliations, as indicated on the title page, should include all corporate affiliations and any funding sources that support the work. Other types of affiliation, including consultantships, honoraria, stock ownership, equity interests, arrangements regarding patents, or other vested interests should be disclosed in the Acknowledgments section.

               References.

Letters to the Editor(s):
Letters to the Editor(s) are welcomed, but with a 500 word limit and no more than one (1) table OR figure, and with a maximum of four (4) references.

 

TABLES AND ILLUSTRATIONS

Use Arabic numerals to number tables. Do not repeat information that is given in the text, and do not make a table for data that can be given in the text in one or two sentences. Provide titles for all tables. Define all acronyms in table footnotes. All other types of table footnotes should be designated using superscript letters, not symbols.

A legend should be supplied for each figure, and all legends numbered consecutively and provided (double spaced) on a separate page at the end of the main text file. All symbol definitions should be in the figure legend, not as a key within the figure. If possible, please use Arial font for figure text. One-column graphs should not exceed 3¼ inches. If a graph must be larger so small data is clearly visible, the graph should not exceed 6½ inches. Anything larger will need to be reduced and data could become illegible. The point size of axis labeling or text within figures should not exceed 12 points.

Figures should be numbered in the order cited in the text. Images should not show the name of a manufacturer or reveal patients’ name(s). Please keep in mind that the figures will be reduced, so please do not submit large figures/graphs that contain small type, as the text within the figure will not be readable after reduction.

Color publication of figures is encouraged, but the cost for color printing must be subsidized by the author(s). Color costs apply to all manuscripts, including those invited, unless the contributor has made prior arrangements with the Publisher. Please consider these costs when preparing your manuscript for submission. For further details, contact the Publisher.

Please follow these instructions carefully when preparing figure files for uploading:

Do NOT include any illustrations as part of your text file.

Line illustrations must be submitted at 600 DPI.

Halftones and color photos should be submitted at a minimum of 300 DPI.

Power Point files cannot be uploaded on to Manuscript Central.

Save art as either TIFF or EPS files. JPEG files are for screen representation-quality only and will print very poorly during the printing process. To ensure proper print quality, please submit only TIFF or EPS files.

Color art must be saved as CYMK, not RGB. (NB: If RGB files are submitted, the files will be converted to CYMK and some color variation will occur.)

• When naming your figure files, please label them with the author’s last name, followed by a period (.), and then list the figure number. Ex: Smith.Fig1.tif. Label figures and tables inside the files in addition to naming the file with the figure or table number. (ie: When figures or table files are opened, the figure or table number should appear inside the file.)

NOTE:  Supplemental Information will not be copyedited or typeset; they will be posted online-only as they were supplied.

Protocol Table. Authors should include a Protocol Table having the general format as shown below to supplement the Methods section.   This format will allow the optimized HTS or other assay protocols with specific comments for each step to be presented in a straightforward manner, and allow ADT to establish a consistent protocol format.

 

Figure layout.  Figures should be on a white background, and must avoid excessive boxing, unnecessary color, a title on the figure itself, spurious decorative effects (such as three-dimensional ‘skyscraper’ histograms). Do not use a gray or dark background for histograms, and if possible prepare them in a professional graphing program such as Prism, Origin, etc. that matches the presentation format of, for example, dose-response plots.

Concentration response plots. Concentration or dose-response curves should be plotted using a logarithmic x-axis scale for effector (e.g., compound or ligand) concentration and a linear y-axis scale for the effect being measured (e.g., readout from plate reader, percent activity relative to control). In the case of replicate determinations, each point should represent the mean, and error bars should be used to show the SD or SEM. Points may be joined by a line or superimposed on a curve fit obtained by non-linear regression. The figure legend should report the number of replicates, the error calculation used (e.g., SD or SEM), and the type of curve fit. 

This journal’s conventional concentration response curve nomenclature is “Log [cpd], M”. Plots may contain symbol legend within the plot itself, however this information must be also contained within the figure legend (see example below). In general, please differentiate multiple curves on a plot by the type of data point symbol.  Avoid use of color if possible.

Examples below show acceptable figure layouts for the figure legend below. 

Figure 1. Dose-response of active and inactive analogs of two compound series. The inhibition of esterase activity was determined for two representative compounds from the benzthiazol and quinazoline series. The IC50 of the active benzthiazol cpd 123 () was 420 ± 18 nM and the inactive stereo isomer, cpd 124 (  ), had no effect at the highest tested concentration of 6 uM.  The IC50 of the active quinazoline cpd 225 ()  was 677± 30 nM, and the inactive ester, cpd 226 ( ∇ ),  had no effect at the highest tested concentration of 6 uM. The data presented are means +/- SEM of triplicate wells (n=3). 

Bar graphs. Please standardize all figures using a professional graphing software package (e.g. Prism Graphpad). Please do not use Excel for graphing if possible. For bar graphs, use the following patterns, solid, open, and hashed with three or less different conditions (see below); for an additional fourth bar reverse hash lines. Use the finest line settings (e.g. ½ point) when option is available.  Avoid use of color in bar graphs.

C O R R E C T    L I N E    T H I C K N E S S

 

  

I N C O R R E C T    L I N E    T H I C K N E S S

  

 

Error bars and definition. All Figures displaying error bars (e.g., bar graphs, dose-response curves) must include in the figure legend a sentence describing how the error was determined, for example "The data presented are means +/- SEM of triplicate wells (n=3)", or "Error bars represent standard error of n=4 values", etc.

Error measurements must also accompany all reported dissociation/association constants, kinetic parameters (e.g. Km, Vmax) and IC50, e.g. IC50 = 8 ±1 uM.   

Z' factor. All reported Z-factors must include within the paper specifically what ‘signal’ and ‘background’ or ‘inhibited’ conditions were used to obtain the data used to calculate this value. In addition, and importantly, how many wells were used to calculate the Z'? For a 96-well plate ideally half the wells (n=48) would be used as ‘background’ or ‘inhibited’ and the other half (n=48) as the ‘stimulated’ or ‘max signal’. A typical experiment in the standard 96-well format should be shown. Example is below.  

 

 

Chemical Structures.Structures should be produced with the use of a drawing program such as ChemDraw. Authors using the current versions of ChemDraw will find the necessary parameters incorporated into this program (“ACS Document 1996”).

Cover Submissions. Outstanding color artwork is encouraged for possible use on the cover. The ADT cover is composed of three elements: (1) a background that fills the cover space, (2) a foreground image, and (3) the chemical structure that occupies the top right corner of the cover. Please provide a few sentences describing the assay or technology and a single sentence for each element, see example below for guidance. DO NOT REPEAT ENTIRE FIGURE LEGEND FROM ARTICLE. Authors are encouraged to submit choices of images and/or figures that would make for an interesting cover. Once the editors select the cover art, our graphic artist creates the cover.  See the Cover Art Gallery for examples of previous covers.

 ASSAY and Drug Development Technologies E
xample Caption:  LacZ expression in transgenic animals is typically assessed in vitro in tissue slices using X-gal, which is cleaved by the LacZ gene product to yield an insoluble blue cleavage product. Zhang and colleagues have developed a method for in vivo assessment LacZ expression in transgenic animals using DDAOG, which is cleaved by the LacZ gene product to yield a cleavage product with far-red fluorescence. The fluorescent product is detected using an in vivo optical imaging system. Foreground: schematic of in vivo optical imaging system (illustrator: Daniela Bednarova). Background: GPR56KO/LacZ mouse kidney medulla stained with X-gal.Upper right chemical structure: DDAOG (7-hydroxy-9H-(1,3-dichloro-9,9-dimethylacridin-2-one)-b-D-galactopyranoside).
 

Animal and Human Tissue Guidelines

Please include within Materials and Methods your institute's compliance statements for animal experimentation and handling of human tissue. Examples:

Use of Animals. Animal experimentation complied with local and national requirements, including the UK Coordinating Committee on Cancer Research guidelines for the welfare of animals in experimental neoplasia.37

37. Workman P, Twentyman P, Balkwill F, Balmain A, Chaplin D, Double J, Embleton J, Newell D, Ramond R, Stables J, Stephens T: United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia [second edition]. Br J Cancer 1998;77:1–10.

Handling of human tissue. Handling of human DRG tissue was carried out according to legal provisions and rules of the medical faculty of the Innsbruck Medical University.

COMPARATIVE STUDIES BETWEEN ASSAY TECHNOLOGIES

Authors preparing manuscripts containing comparisons of assay technologies are advised that the following points will be considered during peer-review: 

• A Z-factor analysis along with the formula used to calculate the Z-factor must be included, especially if formats are fundamentally different, e.g., a ratiometric vs. a single readout assay. The authors should describe the plate format, number of wells, and plates used to obtain this statistic.

• Discrepancies in the ability to reproduce an activity of published controls must be carefully explained. Particular attention should be paid to experimental parameters and reagent properties that differ from those previously reported (e.g., enzyme specific activity, protein or compound purity).

• Product comparisons may be supported by reference to data from peer-reviewed publications. In the absence of prior peer reviewed publication, data to support (or critique) a specific product should be presented in the paper so that it will be subjected to peer review upon submission to Assay and Drug Development Technologies. Selective use of literature to support an advantage over an existing technology is inappropriate, as is selective omission of literature references to create the appearance of a competitive advantage. In general, existing literature relevant to the reported assay technology should be cited comprehensively, and negative and positive aspects should be discussed in a scientific and unbiased manner.

• Vendor manuals available online may be referenced when a method is based on a commercial kit or performed ‘‘according to the manufacturer’s instructions.’’ Reviewers, however, may require details to be included in the manuscript. Data in manuals, application notes, and posters that have not been subjected to peer review may not be used to compare one product with another or to support a central argument in a paper.

• The use of promotional or marketing-like statements is not permitted. Examples of marketing terminology:  "XYZ Biosciences has recently launched the first commercially available version...."   "For higher throughput a plate based version, Speedy Workstation, is available. With this device screening of large compound libraries will be possible without loss of data quality." In addition please remove all terms of novelty from the title and text (e.g., novel, innovative, unique).  

REFERENCES

All references must be cited in the text using a superscript Arabic number. Arrange the reference list in numeric order as cited in the text.   When there are more than six authors, list the first three followed by “et al.”  Abbreviate journal names according to Serial Sources for the BIOSIS Data Base (BioSciences Information Service, 1992). References should be presented in the following style: Journal citation: Ferrer M, Hamilton A, Inglese J: A PDZ domain-based detection system for enzyme assays. Analyt Biochem 2001;301:207–216. Book citation: Kahn M: High Throughput Screening for Novel Anti-Inflammatories. Birkhauser, Basel, Switzerland, 2000. Chapter in edited book: Banks M: Automation and Technology for HTS in Drug Development. In: Approaches to High Throughput Toxicity Screening (Atterwill CK, Purcell W, Goldfarb P, eds.), pp. 9–30. Taylor & Francis, London, United Kingdom, 1999. Web sites: Name of web page. Web address. (Last accessed on [date]). Example: DOE Human Genome Program Research. Available at: www.ornl.gov/sci/techresources/Human_Genome/research/research/shtml . Last accessed August 31, 2005.

When data from an unpublished source are given, supply the researcher’s name and institution, and the year in which the research was conducted.  If the work is in press, give the journal in which it is to be published.

This journal is included in EndNote. You may download the EndNote style file herePlease note, however, that the Publisher of this journal does not provide technical support for EndNote. For assistance with the program, contact EndNote directly (http://www.endnote.com/).

PERMISSIONS

The author must obtain written permission from the publisher of the journal or book concerned for the reproduction of figures, tables, etc., from copyrighted materials.

The publication from which the figure or table is reprinted must be listed as a complete reference in the reference list.

An appropriate credit line should be included in the figure legend or table footnote, and full publication information should be included in the reference list.

 

Manuscripts should be submitted with the understanding that they have neither been published, nor are under consideration for publication elsewhere, except in the form of an abstract. Prior abstract publications should be described in the form of a footnote to the title. Authors with papers under consideration elsewhere having significant overlap to those submitted to ASSAY and Drug Development Technologies should provide copies of such manuscripts to the editor. The editors maintain the option to reverse an acceptance decision should an apparent issue with publishing policies or scientific content arise. Published manuscripts become the sole property of the Journal and will be copyrighted by Mary Ann Liebert, Inc. By submitting a manuscript to the Journal, the author(s) agree(s) to each of the above conditions. In addition, the author(s) explicitly assign(s) any copyrighted ownership he/she (they) may have in such manuscript to the Journal.

It is critical to ensure the accuracy of ALL authors’ email addresses when uploading submissions to Manuscript Central to ensure the proper delivery of all email communications.

FAILURE BY ALL AUTHORS TO SUBMIT THIS FORM MAY RESULT IN A DELAY OF PUBLICATION.

The corresponding author is responsible for communicating with coauthors to make sure they have completed the online copyright form. Authors not permitted to release copyright must still return the form acknowledging the statement of the reason for not releasing the copyright.

 

AUTHORSHIP

It is the submitting author’s  responsibility to ensure the accuracy and inclusion of all contributing authors’ names and affiliations upon submission. Once a paper is accepted for publication, changes in authorship while the paper is in production – including page proofs – are NOT permitted. Changes in authorship after publication are strictly prohibited.


page proofs

It is the Journal’s policy that a manuscript has only ONE corresponding author listed on a paper.  This designation should be determined at the time of submission.  Additions to corresponding authors are not permitted after acceptance, in page proofs, or after publication.

Page proofs will be sent to the (one) corresponding author as designated when the manuscript was uploaded to Manuscript Central.  It is the corresponding author’s responsibility to share the page proofs with co-authors and to coordinate all authors’ corrections into one proof.  The Publisher will not accept corrections from multiple authors.

 

REPRINTS


Reprints may be ordered by following the special instructions that will accompany page proofs, and should be ordered at the time the corresponding author returns the corrected page proofs to the Publisher. Reprints ordered after an issue is printed will be charged at a substantially higher rate.

PUBLISHER

ASSAY is owned and published by Mary Ann Liebert, Inc., publishers, 140 Huguenot Street, New Rochelle, NY10801. Telephone: 914-740-2100; Fax: 914-740-2101; E-mail: info@liebertpub.com; Website: www.liebertpub.com 

Our dynamic Author Benefits Program provides you with end-to-end benefits that ensure your hard work pays off and your published manuscript gets the attention it deserves not just upon publication, but permanently.

Liebert Open Access

Ensure maximum visibility, discoverability, and impact for your article with our Liebert Open Access (OA) option

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The Liebert Open Access option enables authors to publish open access in our esteemed subscription-based journals.

The benefits of Liebert Open Access include:

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Copyright and Licensing

If you choose to publish with open access, you will retain copyright of your article and a Creative Commons license will be applied. The liberal Creative Commons Attribution 4.0 (CC-BY) license is the default open access license used at Mary Ann Liebert, Inc., publishers. The CC-BY license permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

At this time we allow authors to choose between the CC-BY or CC-BY-NonCommercial license. A limited number of journals offer NonCommercial licenses exclusively.

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Publishing open access includes an article publication charge (APC) and authors are asked to fill out a short open access order form.  You can pay by credit card or receive an invoice to be returned with payment or via bank transfer. Please remember that traditional subscription journals can carry mandatory or optional author fees. The Liebert Open Access APC does not cover or replace existing publication or author fees.

Publishing biomedical or biotechnology research?

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JOURNAL FEES

  • There are no submission fees to ASSAY and Drug Development Technologies.
  • There no page charges for ASSAY and Drug Development Technologies.
  • Please contact AuthorBenefits@liebertpub.com for costs for publishing images in color.
  • Open Access and Creative Commons licensing options are available. Contact our Open Access Manager for more information.
  • For pricing and purchasing reprints, contact our Reprints Manager.
  • Any fees collected or payments associated with a submitted and/or published paper that is subsequently withdrawn and/or retracted for any reason are non-refundable.

All Mary Ann Liebert, Inc. journals follow the standards, guidelines, and best practices set forth by the -Committee on Publication Ethics (COPE; publicationethics.org), the International Committee of Journal Medical Editors (ICJME; www.icmje.org), the World Medical Association (WMA); www.wma.net) and the American Medical Association (www.ama-assn.org).

ASSAY and Drug Development Technologies is a single-blinded peer-reviewed journal. All submissions are subject to peer review. Upon submission, manuscripts are assessed by an editor for suitability for the journal.  For those that are deemed suitable, a minimum of two expert reviewers in the area of study will be selected to assess the scientific basis and significance of the manuscript. Following peer review, the Editor and/or Associate Editors will determine if the paper should be accepted, require revision, or is unacceptable for publication.

Confidentiality in Peer Review

Editors and reviewers must maintain strict confidentiality of manuscripts during the peer-review process. Sharing a manuscript in whole or in part, outside the scope of what is necessary for assessment, is impermissible prior to an accepted manuscript's official publication date.

Sharing of Materials during Peer Review

Authors must honor any reasonable request for materials, methods, or data necessary to reproduce or validate the research findings during peer review unless it violates the privacy or confidentiality of human research subjects.

Papers Authored by the Editor-in-Chief and/or Associate Editors

The Editor-in-Chief and Associate Editors will recuse themselves from participating in the review process of any manuscript in which there is a potential or actual competing interest.

Self-Citation and Self-Plagiarism

ASSAY and Drug Development Technologies is committed to maintaining the integrity of the peer review process by upholding the highest standards for all published articles. All manuscripts will be processed through plagiarism detection software prior to peer review. Plagiarized manuscripts will be rejected immediately. While a manuscript submission may contain some redundancy in language and content (i.e., Materials and Methods) compared to work previously published by authors, self-plagiarism can infringe upon copyright. To avoid plagiarism, be sure to properly cite and reference all published works. (Deposition of a preprint on a preprint server is not considered as prior publication and will not impact consideration of any submitted manuscript.)

Time in Review

ASSAY and Drug Development Technologies aims to maintain a short, but thorough peer-review process. The average time in review is 45 days.  However, the Editor(s) will strive to expedite manuscript handling if/when special circumstances dictate.

ATTENTION:  To ensure the receipt of all communications from the journal editorial office and publisher, please whitelist the following domains to prevent spam filter detection or non-deliverables:

  • manuscriptcentral.com
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Failure to whitelist these domains may significantly hinder the progress of peer review on submitted manuscripts, and the production process of accepted papers.
 

AUTHORSHIP

Definition of Authorship

Authorship, as defined by the International Committee of Medical Journal Editors, is based on the following criteria:

  • Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND
  • Drafting the work or revising it critically for important intellectual content; AND
  • Final approval of the version to be published; AND
  • Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Non-Author Contributors

Contributors who meet fewer than all four of the above criteria for authorship should not be listed as authors, but they should be acknowledged in the Acknowledgments section with a description of their contribution to the work.

For further information, visit the International Committee of Medical Journal Editors’ website at: http://www.icmje.org/recommendations/browse/roles-and-responsibilities/defining-the-role-of-authors-and-contributors.html

ORCID IDs

All submitting authors are required to complete their submissions using an ORCID identifier. Please visit the ORCID website for more information, or to register.

AUTHORSHIP LIMIT

There is a limit of 35 of authors permitted on a single submission, but in cases where there are 20 or more co-authors, ASSAY and Drug Development Technologies recommends that a collective group or consortium name be provided and the individual authors listed in the Acknowledgements.

CORRESPONDING AUTHOR**

One author should be designated as the corresponding author who will be responsible for communication between the authors and the journal editorial office(s) and publisher. This individual will be responsible for ensuring all authors submit copyright forms and coordinating and responding to page proofs, as well as any managing any other necessary contact during the peer review and/or production processes.

**NOTE: Due to configuration restraints, the submission system permits only one author to be identified as the corresponding author of record. However, we recognize that some submissions call for more than one corresponding author to be noted. In such cases, select one author to be the main point of contact and/or corresponding author for all communications regarding the peer review process of the paper, but on the title page of the manuscript, designate additional co-corresponding authors by including an asterisk after the authors' names in the byline, and include an accompanying footnote on the title page that reads, "*Co-corresponding authors."  Please ensure that the title page of the submission page carries the full affiliation details and email addresses of all authors who should be noted as a corresponding author. If the paper is accepted for publication, the full contact information for all desginated co-authors will be listed at the end of the article as per usual journal style.

WORKING GROUPS / TEAM AUTHORSHIP

Working Groups or Teams may be listed in the manuscript byline, but the entire listing of names and affiliations should be included in the acknowledgment section of the manuscript. Do not list the names in a footnote on the title page.

VARIATIONS OF AUTHORSHIP

It is permissible to list up to three authors as co-first authors, or as contributing equally to the work. Include an asterisk (*) next to the authors' names who are considered as first authors. Include a corresponding footnote, using the asterisk, on the title page that reads, "These authors contributed equally to this work and are considered to be co-first authors."

CHANGES IN AUTHORSHIP

Changes in authorship after submission or acceptance of a paper are strongly discouraged, but the editorial leadership recognizes that in certain circumstances, it may be required. The journal's policy for such cases is as follows:

  • A request to alter authorship must be made in writing from the corresponding author to the Editor-in-Chief, with a detailed explanation for the request, and the names and affiliations of the authors requiring addition and/or deletion.
  • Authorship may be altered after submission or acceptance of a paper ONLY with the expressed written approval of all authors named on the manuscript, as well as the individual(s) being added and/or deleted. The Publisher can provide a form for this, if needed.
  • Upon receipt of the request and all written approvals of all involved parties, the Editor-in-Chief will consider the request, render a decision, and notify the corresponding author.
  • There is a one-year post-publication statute of limitation on requests for alterations in authorship.
  • Post-publication changes or alterations to conference abstracts are prohibited.

ATTENTION: To ensure the receipt of all communications from the journal editorial office and publisher, please whitelist the following domains to prevent spam filter detection or non-deliverables:

  • manuscriptcentral.com
  • amazonses.com
  • liebertpub.com

Failure to whitelist these domains may significantly hinder the progress of peer review on submitted manuscripts, and the production process of accepted papers.

EXCLUSIVITY

Manuscripts should be submitted with the understanding that they have neither been published, nor are under consideration for publication elsewhere, in the same form or substantially similar form, except in the form of a conference abstract.  If work was presented at a conference, supply the name, date, and location of the meeting as a footnote on the title page of the submission.

USE OF ENGLISH LANGUAGE

All submissions must be in English. Appropriate use of the English language is a requirement for review and publication in ASSAY and Drug Development Technologies. For authors whose native language is not English, we recommend using a service that will aid in the translation and rewriting of material into correct and proper English usage. The Publisher offers this service for a fee prior to official submission. For more information, please contact: Editing@liebertpub.com Please note that employing the use of the Publisher's service is not required and using it, or any other language editing service, does not guarantee acceptance of any paper. All submissions are subject to peer review.

AUTHOR DISCLOSURE STATEMENTS

  • Competing Interests. A competing interest exists when an individual (or the individual's institution) has financial or personal relationships that may inappropriately influence his actions. These competing interests may be potential or actual, financial or other.
  • Personal Financial Interests. Stocks or shares in a company that may gain or lose financially from publication of the article; consulting fees or other remuneration from an organization that may gain or lose financially from publication of the article; patents or patent applications that are owned by or licensed to companies/institutions that may gain or lose value from publication of the article.
  • Funding. Research support by organizations that may gain or lose financially from publication of the article. This support includes salary, equipment, supplies, honoraria, reimbursement or prepayment for attending symposia, and other expenses.
  • Employment. Recent (within the past 5 years), current, or anticipated employment by an organization that may gain or lose financially from publication of the article.
  • Other Competing Interests. Any personal relationship which may inappropriately affect the integrity of the research reported (by an author) or the objectivity of the review of the manuscript (by a reviewer or Editor), for example, competition between investigators, previous disagreements between investigators, or bias in professional judgment.

SELF-CITATION AND SELF-PLAGIARISM

ASSAY and Drug Development Technologies is committed to maintaining the integrity of the peer review process by upholding the highest standards for all published articles. All manuscripts will be processed through plagiarism detection software prior to peer review. Plagiarized manuscripts will be rejected immediately. While a manuscript submission may contain some redundancy in language and content (i.e., Materials and Methods) compared to work previously published by authors, self-plagiarism can infringe upon copyright. To avoid plagiarism, be sure to properly cite and reference all published works.

AFFILIATIONS

Authors should identify as their institution(s) the facility where the work was performed and executed.  Changes in an author’s affiliation after the work was completed but prior to the submission or publication of the manuscript should be noted by including an asterisk as a superscript to the name in the author listing, as well as a corresponding footnote on the title page indicating “Current Address” listing the new affiliation.   Corrections to affiliations or contact information due to relocation after publication is not permitted.

REPRINTS

Reprints may be ordered by following the special instructions that will accompany the proofs and should be ordered at the time the corresponding author returns the corrected page proofs to the Publisher as reprints ordered after the issue is printed will be charged at a substantially higher rate.

Word limits do NOT pertain to the abstract, disclosure statements, author contribution statements, funding information, acknowledgments, tables, figure legends, or references.

Original Articles
•    3,000-word limit
•    Unstructured abstract of no more than 250 words
•    Maximum total of eight (8) figures and/or tables

Review Articles
•    8,000-word limit
•    Unstructured abstract of no more than 250 words
•    Maximum total of ten (10) figures and/or tables

Perspectives
•    1,500-word limit
•    Unstructured abstract of no more than 100 words
•    An Introduction and a Conclusion are mandatory
•    Maximum total of three (3) figures and/or tables
•    Maximum of 25 references

Editorials
•    1,000-word limit
•    No abstract
•    No figures or tables
•    Maximum of 10 references

Letters to the Editor
•    500-word limit
•    No abstract
•    May include one figure OR table
•    Reference citations are identical in style to those of full original articles, but should not exceed five (5).

 

INTERNAL REVIEW BOARD APPROVALS/WAIVERS

(as described and defined on the World Medical Association's website)

When reporting research involving human data and/or  handling of human tissue, authors should indicate whether the procedures followed have been assessed by the responsible review committee (institutional and national), or if no formal ethics committee is available, were in accordance with the Declaration of Helsinki as revised in 2013. If doubt exists whether the research was conducted in accordance with the Helsinki Declaration, the authors must explain the rationale for their approach and demonstrate that the institutional review body explicitly approved the doubtful aspects of the study. Approval by a responsible review committee does not preclude editors from forming their own judgment whether the conduct of the research was appropriate.

If the study is judged exempt from review, a statement from the committee is required. Informed consent by participants should always be secured. If not possible, an institutional review board must decide if this is ethically acceptable. This information should be outlined in the cover letter accompanying the submission, and in a sentence declaring adherence should be included in the Materials and Methods section of the manuscript.

ETHICS OF EXPERIMENTATION

All articles involving the use of human fetuses, fetal tissue, embryos, and embryonic cells must adhere to the US Public Law 103–41, effective December 13, 2001. (http://ethics.od.nih.gov/).

ETHICAL TREATMENT OF ANIMALS

All peer-reviewed submissions containing animal experiments must comply with local and national regulatory principles and contain a statement in the Materials and Methods section. Please include your institute's official compliance statement(s) for animal experimentation, or state whether national regulatory guidelines for the care and use of laboratory animals were followed.  Include a corresponding citation and a reference, if applicable.

Example of in-text wording:

Use of Animals. Animal experimentation complied with local and national requirements, including the UK Coordinating Committee on Cancer Research guidelines for the welfare of animals in experimental neoplasia.37
 
Sample of corresponding reference:

37. Workman P, Twentyman P, Balkwill F, et al.: United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia (second edition). Br J Cancer 1998;77:1–10.

For further information, consult the World Medical Association’s website.

AUTHOR CONFIRMATION STATEMENTS

Authors are required to include a statement of responsibility in the manuscript after the Acknowledgments section that specifies the contribution of each author listed on the submission. If a paper is accepted for publication, these statements are published as part of the article. 

AUTHOR DISCLOSURE STATEMENTS

All authors included on a submission must disclose any actual or potential conflicts of interest that may affect the author’s relationships and activities, directly or indirectly, related to the work.  Consult

  • Competing Interests. A competing interest exists when an individual (or the individual's institution) has financial or personal relationships that may inappropriately influence his actions. These competing interests may be potential or actual, financial or other.
  • Personal Financial Interests. Stocks or shares in a company that may gain or lose financially from publication of the article; consulting fees or other remuneration from an organization that may gain or lose financially from publication of the article; patents or patent applications that are owned by or licensed to companies/institutions that may gain or lose value from publication of the article.
  • Funding. Research support by organizations that may gain or lose financially from publication of the article. This support includes salary, equipment, supplies, honoraria, reimbursement or prepayment for attending symposia, and other expenses.
  • Employment. Recent (within the past 5 years), current, or anticipated employment by an organization that may gain or lose financially from publication of the article.
  • Other Competing Interests. Any personal relationship which may inappropriately affect the integrity of the research reported (by an author) or the objectivity of the review of the manuscript (by a reviewer or Editor), for example, competition between investigators, previous disagreements between investigators, or bias in professional judgment.

For further information, visit the Disclosure of Financial and Non-Financial Relationships and Activities, and Conflicts of Interest of the International Committee of Medical Journal Editors website.

  •  

COPYRIGHT AGREEMENT FORM

Upon acceptance of any manuscript, all authors will receive an email with detailed instructions and a unique, author-specific link to access and complete our online Copyright Agreement form. It is critical to ensure the accuracy of ALL authors' email addresses when uploading submissions to Manuscript Central to ensure the proper delivery of all email communications. FAILURE BY ALL AUTHORS TO SUBMIT THIS FORM WILL RESULT IN A DELAY OF PUBLICATION. The corresponding author is responsible for communicating with coauthors to ensure they have completed the online copyright form. Authors not permitted to release copyright must still return the form acknowledging the statement of the reason for not releasing the copyright. Copyright forms may also be completed by logging in to the system using an author's credentials. After logging on, click on Author Center and complete the forms located under "Manuscripts I Have Coauthored."

Published manuscripts become the sole property of the Journal and will be copyrighted by Mary Ann Liebert, Inc., unless alternate arrangements are made prior to publication, including CC-BY licensing (see below). By submitting a manuscript to the Journal, the author(s) agree(s) to each of the above conditions. In addition, the author(s) explicitly assign(s) any copyrighted ownership he/she (they) may have in such manuscript to the Journal.

OPEN ACCESS / CC-BY LICENSING

ASSAY and Drug Development Technologies is a subscription-based peer-reviewed journal with Open Access options. Creative Commons CC-BY and CC-BY-NC licensing is available for all articles published open access for a standard Article Processing Charge (APC) of $3,200.00 USD. Please contact our Open Access Manager to order open access for your article. Learn more about open access publishing on our website.

PERMISSIONS

When reproducing copyrighted material such as figures, tables, or excerpted text, the author(s) of the submitted paper must obtain permission from the original publisher and submit it concurrently with the manuscript. The publication from which the figure or table is taken must be listed in the reference list. Finally, a footnote to a reprinted table or the legend of a reprinted figure should read, "Reprinted by permission from Jones et al." and list the appropriate reference. All permissions must be supplied at the time of submission.  Authors are responsible for any fees that may be incurred by securing permission to reproduce or adapt material from other published sources.

REUSE OF MATERIAL POSTED ON SOCIAL MEDIA

As material posted on social media platforms is usually not peer-reviewed content, it is not permitted as an official citation and/or reference.

Mary Ann Liebert, Inc., publishers permits the use of accepted pre-published manuscripts for the sole purpose of pitching to news organizations under strict embargo, and with the approval of and expressed collaboration with the publisher. A watermarked PDF version of the article (not a Word document or any other editable version) may be shared only with named, personal contacts at trusted news sources upon request. News sources must be informed upon delivery of the PDF that the manuscript is for reference-only purposes and can be used only in preparation of their news coverage of the article. It is strictly prohibited to publicly share, post, or otherwise distribute the PDF in any media format. Upon official publication of the article, news organizations must link directly to the published article on the publisher’s journal website. To coordinate publication timing and press efforts, please contact the Director of Marketing, Kathryn Ryan (kryan@liebertpub.com).

DATA SHARING

ASSAY and Drug Development Technologies strongly advocates the sharing and archiving of the data and any other artifacts that define and support the results stated in a manuscript in a suitable public repository (in accordance with valid privacy, legal, and ethical guidelines). A data availability statement should be included in the manuscript (in the Methods section or as a separate section at the end of the manuscript), describing the location of the data, with details on how it can be accessed as well as any licensing information. If the data is not publicly available or accessible, that information should also be provided.

Datasets should be cited in the reference list by Author (Year). Title. Publisher. Identifier/DOI.

Important: Please check with your funding agencies to ensure that are you following their data sharing polices. If your funding agency has additional requirements exceeding our policy, you must follow the requirements of your funder.

PREPRINT SERVERS

A preprint is a complete draft of a research paper that is shared on a public preprint server prior to submission to a journal for peer review.
 
Mary Ann Liebert, Inc., allows for papers that were previously deposited on preprint servers to be submitted to our journals, with the proviso that the author updates any preprint versions with a link to the final published article.  All submissions are subject to peer review and allowing the submission of preprint manuscripts does not guarantee publication in any Mary Ann Liebert, Inc., journal.
 
The submitting author of a paper that was previously deposited to a preprint server should include a disclosure on the title page of the manuscript indicating the name and website of the server and include the DOI number of the preprint.
 
Referencing/citing non-peer-reviewed material that is found on any preprint server is generally discouraged by Mary Ann Liebert, Inc., journals, but if it is necessary, the citation must make it clear that the content is not officially published in a journal, and can only be found on a preprint server.

 

RESEARCH FUNDER COMPLIANCE (FundRef)

Upon submission of a manuscript, the submitting agent will have an opportunity to enter funding/grant information. If funding information is entered correctly, the publisher will deposit the funding acknowledgements from the article as part of the standard metadata to FundRef. The entered information should include funder names, funder IDs (if available), and associated grant numbers.  Special care should be taken when entering this information to ensure total accuracy. (See https://www.crossref.org/services/funder-registry/ for a listing of more than 13,000 international funding agencies.)

GOVERNMENT FUNDED RESEARCH

ASSAY and Drug Development Technologies is fully NIH-, HHMI-, RCUK, and Wellcome Trust-compliant.

OPEN ACCESS

Our open access publishing solutions allow you to comply with the open access policies of your institution, government, and funding body. If you are employed or funded by the National Institute of Health (NIH), the Wellcome Trust, Research Councils UK (RCUK), or Howard Hughes Medical Institute (HHMI), you can find more information below:

  • NIH and HHMI Public Access Policy–In order to assist our authors who have NIH funding to comply with this policy, Mary Ann Liebert, Inc. publishers will deposit the final paginated version of the published article to PubMed Central (PMC) on behalf of the authors after a 12-month embargo period. Authors need not take any action. This service is provided free of charge. Authors who wish to remove the 12-month embargo period are encouraged to consider publishing with Open Option.
  • Wellcome Trust Policy–To easily comply, you can choose to have your article published open access under the Creative Commons Attribution (CC BY) license. The publication charge will be covered by the Wellcome Trust.
  • Research Councils UK (RCUK)–To easily comply, you can choose to have your article published Open Access under the Creative Commons Attribution (CC BY) license. The publication charge will be covered by the RCUK.

ATTENTION: To ensure the receipt of all communications from the journal editorial office and publisher, please whitelist the following domains to prevent spam filter detection or non-deliverables:

  • manuscriptcentral.com
  • amazonses.com
  • liebertpub.com

Failure to whitelist these domains may significantly hinder the progress of peer review on submitted manuscripts, and the production process of accepted papers.

POST-ACCEPTANCE / PRODUCTION

All accepted manuscripts will go through copyediting, typesetting, figure sizing and placement, author proofing, corrections, revisions (from corrected proofs), online-ahead-of-print release, and lastly, issue assignment. Depending on the length and complexity of any accepted submission, these steps typically take 3-6 weeks from acceptance.  Changes or alterations to a submission are not permitted after acceptance, but should be addressed in page proofs.

PAGE PROOFS

Page proofs will be sent to the corresponding author as designated in Manuscript Central when the manuscript was submitted. It is the corresponding author's responsibility to share the page proofs with co-authors, if desired, and to coordinate all authors' corrections into one proof. The Publisher will not accept corrections from multiple authors/sources.

AUTHOR RESPONSE TO GALLEY PROOF

  • The corresponding author is responsible for returning corrected galley proofs generally within 72 hours of receipt.
  • If the corresponding author does not respond within that timeframe, the manuscript may be delayed in the publication schedule, or published as is, at the discretion of the Editor and Publisher.
  • If the corresponding author expects to be unavailable during the time the manuscript is in production, the publisher should be provided with an alternate contact. 
  • Only corrections directly related to errors in typesetting and/or layout will be allowed.
  • Any requested changes related to content, or that alter the outcome of a study, will require the approval of the Editor, and may require further peer review.

REPRINTS

Reprints may be ordered by following the special instructions that will accompany the proofs and should be ordered at the time the corresponding author returns the corrected page proofs to the Publisher as reprints ordered after the issue is printed will be charged at a substantially higher rate.

POST-PUBLICATION CORRECTIONS

In the event an error is discovered after publication of an article, the corresponding author should submit the correction in writing to the editorial office for consideration.  After editor approval, alterations will be made to the online version of the article, and if the errors are significant, an official correction statement will be issued.

  • Changes to author affiliations or contact details due to relocation after publication are not permitted.
  • Corrections to meeting abstracts will be made only to the online version.  The Journal does not issue formal correction statements for corrections to meeting abstracts, regardless of the nature of the correction.
  • Correction Statements/Errata to published articles that require the reproduction of color figure(s) and/or table(s) may incur additional costs to the author(s).

RETRACTIONS**

The journal and its publisher are committed to upholding the proper protocols and established standards of peer review.  Published papers found to be in violation of any of the misconduct noted above, or in the accepted principles of peer review and scientific publishing, will be officially retracted from the literature.  An official retraction notice explaining in full detail the circumstances surrounding the need for a retraction.

**Any publication fees for retracted and/or withdrawn articles are nonrefundable in any circumstance.

Policy Statement:
Retraction Notices / Expressions of Concern

The Publisher is committed to protecting the integrity of the public scientific record by sharing reasonable concerns with authorities who are in the position to conduct appropriate investigations into any reported allegations. As such, all allegations of misconduct will be referred to the Editor-in-Chief of the Journal who in turn will review the circumstances, possibly in consultation with Executive Editors, Senior Editors, Associate Editors, and/or other members of the editorial board as needed.  Initial investigations and fact-finding will include a request to all involved parties to state their case and explain the circumstances in writing. In questions of research misconduct centering on methods or technical issues, the Editor-in-Chief may confidentially consult experts who are blinded to the identity of the individuals, or if the allegation is against an Editor, an outside expert. The Editor-In-Chief and/or the Publisher may consult with our Ethics Editor(s) and will arrive at a conclusion as to whether there is enough reasonable evidence that the possibility of misconduct occurred.

When allegations arise, the peer review and publication process of the manuscript in question will cease while the process described herein is researched. The investigation will be taken to completion even if the paper is withdrawn by the authors or Editor(s). In the case of allegations against reviewers or editors, they will be replaced in the review process while the matter is investigated.  If the paper is still under peer review, the Editor-in-Chief reserves the right to withdraw the paper from consideration to the Journal.

If the accusation is with regards to a published paper, the Journal/Publisher reserves the right to publish an official “Expression of Concern” statement while the investigation is still underway.  This statement will contain the full circumstances of the complaint and will be placed directly above the published Abstract in the online version of the article.  If the investigation is not resolved by the time the next print issue of the journal is to be published, the Expression of Concern will be published as official content in the print issue.

If the investigation determines clear misconduct, the Editor-in-Chief and Publisher will officially retract the paper from the Journal and the scientific record by publishing a formal Retraction Notice both online and in print. This notice will contain all relevant details of the accusation, investigation, and the resulting conclusions.

The official Retraction Notice will replace the abstract in the online version of the article as well as in the PDF.  In addition, each page of the PDF will be watermarked with “Retracted.” The Retraction will be delivered to all associated indexing services affiliated with said journal (i.e. PubMed Central, PubMed/MEDLINE, Web of Science, etc.).

In the case where an investigation determines that no misconduct occurred, the Expression of Concern will be updated accordingly but will remain intact as part of the article and will not be removed so that readers will be notified that concerns were raised.

Editors, authors, or reviewers who are found to have engaged in scientific misconduct will be removed from further association with the Journal and reported to their institution.

Every attempt will be made to keep all allegations confidential.

STUDY DESIGN AND ETHICS

RESPONDING TO ALLEGATIONS OF POSSIBLE MISCONDUCT

The Publisher is committed to helping protect the integrity of the public scientific record by sharing reasonable concerns with authorities who are in the position to conduct an appropriate investigation into an allegation. As such, all allegations of misconduct will be referred to the Editor-In-Chief of the Journal who in turn will review the circumstances, possibly in consultation with associate editors and/or members of the editorial board. Initial fact-finding will usually include a request to all the involved parties to state their case and explain the circumstances in writing. In questions of research misconduct centering on methods or technical issues, the Editor-In-Chief may confidentially consult experts who are blinded to the identity of the individuals, or if the allegation is against an editor, an outside expert. The Editor-In-Chief will arrive at a conclusion as to whether there is enough reasonable evidence that the possibility of misconduct occurred.

When allegations concern authors, the peer review and publication process for the manuscript in question will cease while the process described herein is researched. The investigation will be taken to completion even if the authors withdraw their paper. In the case of allegations against reviewers or editors, they will be replaced in the review process while the matter is investigated.

Editors or reviewers who are found to have engaged in scientific misconduct will be removed from further association with the Journal, and reported to their institution.

If an inquiry concludes there is a reasonable possibility of misconduct, the Editor-in-Chief will retract the paper from the Journal and the scientific record. If the paper is still under peer review, the Editor-in-Chief will withdraw the paper from consideration to the Journal.

All allegations will be kept confidential.

DEFINITIONS OF SCIENTIFIC MISCONDUCT

Mary Ann Liebert, Inc., publishers follows the guidelines and rules regarding scientific misconduct put forth by the Committee on Publication Ethics (COPE), the International Committee of Medical Journal Editors (ICMJE), and the Office of Research Integrity (ORI).

Scientific misconduct and violation of publishing ethics vary and can be intentionally or unintentionally perpetrated. Some examples of misconduct and violations include, but are not limited to, the following:

  • Scientific Misconduct: Fabrication, falsification, concealment, deceptive reporting, or misrepresentation of any data constitutes misconduct and/or fraud.
  • Authorship Disputes: Deliberate misrepresentation of a scientist's contribution to the published work, or purposefully omitting the contributions of a scientist.
  • Misappropriation of the ideas of others: Improper use of scholarly exchange and activity may constitute fraud. Wholesale appropriation of such material constitutes misconduct.
  • Violation of generally accepted research practices: Serious deviation from accepted practices in proposing or carrying out research, improper manipulation of experiments to obtain biased results, deceptive statistical or analytical manipulations, or improper reporting of results constitutes misconduct and/or fraud.
  • Material failure to comply with legislative and regulatory requirements affecting research: Including but not limited to serious or substantial, repeated, willful violations of applicable local regulations and law involving the use of funds, care of animals, human subjects, investigational drugs, recombinant products, new devices, or radioactive, biologic, or chemical materials constitutes misconduct.
  • Conflict of Interest: Nondisclosure of any conflicts, direct or indirect, to the Journal which prevents you from being unbiased constitutes misconduct.
  • Deliberate misrepresentation: of qualifications, experience, or research accomplishments to advance the research program, to obtain external funding, or for other professional advancement constitutes misconduct and/or fraud.
  • Plagiarism: Purposely claiming another's work or idea as your own constitutes misconduct and/or fraud.
  • Simultaneous Submission: Submitting a paper to more than one publication at the same time constitutes misconduct.

RETRACTIONS

The journal and its publisher are committed to upholding the proper protocols and established standards of peer review.  Published papers found to be in violation of any of the misconduct noted above, or in the accepted principles of peer review and scientific publishing, will be officially retracted from the literature.  An official retraction notice explaining in full detail the circumstances surrounding the need for a retraction.

Three versions of the article format versions are referenced in the below policy guidelines:

•    Original Submission: The article version that is submitted by the author for consideration, before peer review.
•    Accepted Version: The article version that has been formally accepted after peer review, prior to any typesetting for the journal. This is the version accepted by the editor, before proofs, corrections, and typesetting. Also known as the “raw” accepted version of a manuscript.
•    Article of Record: This article version is the “version of record” that has been formally copyedited, typeset, and published online epub ahead of print and/or in a journal issue. It is the same version published in the “Online Now” section of the journal website.

Self-Archiving Policy

Mary Ann Liebert, Inc., publishers offers authors many options and opportunities to self-archive their work. Self-archiving of work is also referred to, or known as, publishing “Green Open Access”.

Authors can self-archive the original submission version of their article on any website or repository without embargo.

Additionally, authors can self-archive the accepted version of their article on their personal websites or institutional repositories only, without embargo. Any archiving of the accepted version for inclusion in subject-based repositories, such as PubMed Central (PMC), should follow the requirements of the funder of the work.  

Authors are not allowed to publish or self-archive the article of record on any website, social media platform, or repository without permission from Mary Ann Liebert, Inc., publishers, unless they publish their paper Gold Open Access (OA). Learn more about publishing your work Open Access here.

Mary Ann Liebert, Inc., publishers’ society partners or associated affiliates may set self-archiving policies independently, outside of the below -mentioned general policies. Authors should refer to the copyright policy of their chosen journal, which can be found on the Journal Collection Page or by contacting the specific journal editorial office directly. In addition, specific funding organizations have separate agreements and authors should refer to the policies of those specific funding agencies prior to the submission of their manuscript.

Original Submission Version

The original submission version of an article is the author's version that has not been peer reviewed.

This version may be placed on:

•    The author's personal website
•    The author's company or institutional repository or archive
•    Any not-for-profit subject-based preprint servers or repositories

Self-archiving of the original submission version is not subject to an embargo period.

If your submission is formally accepted after peer review in one of our journals, authors must include an acknowledgement of acceptance for publication on all archive sites and, following online publication, authors must include the following notice on the first page:

This is the original submission version (pre-peer review) of the following article: [full citation], which has now been formally published in final form at ASSAY and Drug Development Technologies at [link to final article using the DOI]. This original submission version of the article may be used for non-commercial purposes in accordance with the Mary Ann Liebert, Inc., publishers’ self-archiving terms and conditions.

The original submission version posted may never be updated or replaced with the article of record version unless the author chooses to publish their paper OA under any of the Creative Commons Licenses available through the publisher. If you are interested in publishing your work OA, please feel free to review our Open Access policies and Licenses or contact us.

Accepted Version

Authors may only archive the accepted version of their manuscript on their personal and professional websites, and/or the author’s institutional repository or archive. Any archiving of the accepted version for inclusion in subject-based repositories, such as PubMed Central (PMC), should follow the requirements of the funder of the work. This process may impose additional embargo periods.  

The accepted version may be placed on:
•    The author's personal website
•    The author's company/institutional repository or archive

The accepted version posted must include the following notice on the first page:

This is the accepted version of the following article: [full citation], which has now been formally published in final form at ASSAY and Drug Development Technologies at [link to final article using the DOI]. This original submission version of the article may be used for non-commercial purposes in accordance with the Mary Ann Liebert, Inc., publishers’ self-archiving terms and conditions.

The posted accepted version may never be updated or replaced with the article of record version unless the author chooses to publish their paper Open Access under any of the Creative Commons Licenses available through the publisher. If you are interested in publishing your work OA, please feel free to review our Open Access policies and Licenses or contact us.

Article of Record

The article of record version may never be archived on a website, or in a repository or research network, unless published Gold Open Access under any of the Creative Commons Licenses available through the publisher. If you have questions, please contact us for more information. You can also review our Open Access policies and Licenses.

Funder Requirements

Mary Ann Liebert, Inc. publishers adheres to national and international funder requirements. Various funders, such as the National Institutes of Health (NIH), Wellcome Trust, Howard Hughes Medical Institute (HHMI), The Bill & Melinda Gates Foundation, and UK Research and Innovation (UKRI), for example, have specific requirements for depositing the accepted version and/or the article of record version of the author manuscript in a repository after an embargo period. Authors funded by these organizations should follow the self-archiving terms and conditions of these separate agreements based on the policies of the specific funding institutions. If you have questions, please contact us for more information.

Terms and Conditions for Use of All Self-Archived Article Versions

Authors may use either the original submission version or accepted version in the following ways:

•    For purposes of your own curriculum or teaching, dissertation, thesis, or book provided that all posted versions include the aforementioned notices, and follow all guidelines and requirements specified.
•    To share with researchers and research colleagues provided that such sharing is not for commercial purposes.

The self-archived submitted and accepted versions may only be used in non-commercial capacities. Individual users may view, print, download, and copy self-archived articles, as well as text and data mine the content conditions for non-commercial and non-promotional research and private study purposes, under the following requirements:

•    The authors' moral rights are not compromised and there is clear "attribution" of the author(s) in the shared work.
•    The authors’ integrity remains intact; the work should never be altered in such a way that the author's reputation or integrity may be damaged.
•    Any reuse complies with the copyright policies of the owner of that content.
•    Self-archived content may never be republished verbatim in whole or in part in print or online formats.

 

 

The Office of Foreign Assets Control (OFAC) of the US Department of the Treasury administers and enforces economic and trade sanctions based on US foreign policy and national security goals against targeted foreign countries and regimes, terrorists, international narcotics traffickers, those engaged in activities related to the proliferation of weapons of mass destruction, and other threats to the national security, foreign policy or economy of the United States. (Source: https://www.treasury.gov/about/organizational-structure/offices/pages/office-of-foreign-assets-control.aspx)

Our journal editors welcome contributions from researchers around the world; however, they are also required to follow sanction laws and regulations. Upon the date of this update (August 2020), sanction measures imposed by the United States, United Nations, European Union, and Australia are currently in place against the following countries: Cuba, Crimea, Iran, North Korea, and Syria. Journal editors will treat with caution any submission from a sanctioned country regarding the subject matter and will seek appropriate legal advice from the publisher if necessary.

Papers from sanctioned countries that are submitted to any Mary Ann Liebert, Inc., journal MUST contain a confirmation statement after the conclusion section of the manuscript which indicates that EACH listed author confirms that their research is supported by an institution that is primarily involved in education or research.

For further questions, please contact our Director of Production and Editorial Operations.

ARCHIVING AND PRESERVATION

Mary Ann Liebert, Inc., deposits and archives all publications in Portico for long-term digital preservation. Your article will be easily searchable on Google, Google Scholar, and other search engines.

PUBLISHER

ASSAY and Drug Development Technologies is owned and published by Mary Ann Liebert, Inc., publishers, 140 Huguenot Street, 3rd Floor, New Rochelle, NY 10801; Tel: 914-740-2100; Email: Info@liebertpub.com; Website: www.liebertpub.com/ADT

The views, opinions, findings, conclusions and recommendations set forth in any Journal article are solely those of the authors of those articles and do not necessarily reflect the views, policy or position of the Journal, its Publisher, its editorial staff or any affiliated Societies and should not be attributed to any of them.