Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy is a peer-reviewed venue for promoting and sharing research rooted in hybridoma technology. It aims at advancing the understanding of the biology and immunology that underscores the utility of antibodies as diagnostics and therapeutics. Paramount to this aim the Journal scope includes research on the biology of B cells, the production of antibodies in terms of antibody descriptions, antibody engineering innovations and their use in diagnosis and therapy. Most importantly our broadened scope includes aspects of biology and immunology at the level of the antibody repertoire, structural biology of antibody and modern omics techniques. Methodologically these areas may include biophysical, biochemical and computational approaches as well as informatics and database development spanning the computational, genomic, and database resources required for analyses. In the area of diagnosis and therapy, preclinical and clinical assessments of antibodies, and formulations that induce or activate antibodies are welcomed. Submitted manuscripts can take the form of original research, short reviews, commentary, and position papers.  All manuscripts will adhere to the Journal guidelines that now include statement of competing interest, and clarification statement of author contribution.  

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy covers:

Diagnostics

• Immunohistochemistry to characterize or identify antigens
• Generation for use in molecular monitoring
• Probes for disease progression
• Marker discovery

Therapeutics

• Antibody based therapies
• Drug delivery systems including antibody-mediated nanoparticles
• Combination Therapies
• Design of Immunopharmaceuticals
• Preclinical models and clinical studies
• Vaccine/Immunization studies

Biology

• Antibodies as tools in Immunology
• Antibodies as probes of structure and cells
• Antibodies as regulatory agents
• Cellular and molecular responses to antibody immunization
• BCR Repertoire Compartments

Genetics

• BCR and Antibody genetics
• Epigenetic influence on antibody response
• Metabolic influence on antibody production
• Repertoire diversification

Antibody-Antigen characterization and molecular basis of recognition

• Characterization, epitope mapping
• New sources for availability of fully characterized antibodies
• Molecular and structural studies of antibody and fragments there of
• Design and development of surrogate antibodies by protein engineering
• Computational/ Informatics based analysis of antibody-antigen interaction

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy is under the editorial leadership of Editor Thomas Kieber-Emmons, PhD, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA, and other leading invers. View the entire editorial board.

Audience: Cell biologists, immunologists, molecular biologists, among others