Information For Authors
- Manuscript Submission Guidelines
- Author Benefits Program
- Open Access Policy
- NIH/HHMI Wellcome Trust Policies
- Self-Archiving Policy
Submitting Your Manuscript
The CRISPR Journal welcomes format-neutral manuscripts for first-time submissions. Newly submitted manuscripts will not be unsubmitted for formatting issues. However, after the initial peer review process, revised submissions must follow correct journal formatting and file guidelines, as described below in the Instructions for Authors. Please note that there are certain compulsory elements (i.e.: IRB approvals, author disclosures, etc.) for all new submissions. Manuscripts submitted without this information will be unsubmitted and the submitting author will be asked to add the required components.
The submitting author is required to complete the submission using an ORCID identifier. Please visit the ORCID website for more information, or to register. You must have an account in ScholarOne for The CRISPR Journal before logging in with an ORCID identifier.
Manuscript Submission Site
Create an Account in ScholarOne
If you do not already have an account in ScholarOne for The CRISPR Journal, you will need to create one. Once you create your account, you may log in to the system to begin your submission. Each listed author on a submission must either have an account, or have one created, in the submission system.
Check the Journal’s PEER REVIEW POLICIES
All authors, including the co-authors, should be responsible for a significant part of the manuscript. All authors and co-authors should have taken part in writing the manuscript, reviewing it, and revising its intellectual and technical content. Any author whose name appears on a manuscript assumes responsibility and accountability for the results.
All Original submissions must contain:
- An Institutional Review Board (IRB) approval (or waiver) statement in the Methods section
- Acknowledgments section (if applicable) after the Conclusion of the manuscript, followed by
- An Author Contribution statement for each listed author, followed by
- An Author Disclosure Statement for each author listed on a submission, even if there are no conflicts to disclose, followed by,
- Funding statement(s), even if there is no funding information to declare.
See FUNDING INFORMATION: COMPLIANCE AND STATEMENTS
Human Subjects: Patient Consent/Release
If applicable, it is incumbent upon the author(s) to obtain patient release statements of permission to reproduce any identifiable images of patients. The Journal does not provide a generic patient release form. Any identifying information should not be published in descriptions or photographs unless the information is essential for scientific purposes and the patient (or parent/guardian) gives written informed consent for publication. Informed consent for this purpose requires that an identifiable patient be shown the manuscript to be submitted. Authors should disclose to these patients whether any potential identifiable material might be available via the Internet as well as in print after publication. Nonessential identifying details should be omitted. Informed consent should be obtained if there is any doubt that anonymity can be maintained. For example, masking the eye region in photographs of patients is inadequate protection of anonymity. If identifying characteristics are de-identified, the manuscript should contain assurances/statements that such changes do not distort scientific meaning.
In keeping with patients' rights of privacy, the Journal does not require the submission of patient consent forms, but instead requires the author(s) to retain and archive all patient consent documentation. Upon submission of a manuscript for review, the authors must make a statement in a cover letter to the Editor/Journal which attests that they have received and archived written patient consent.
All manuscripts must be prepared in accordance with the Uniform Requirements for Manuscripts Submitted to Biomedical Journals.
When submitting your manuscript for peer review, be prepared to:
- Enter the full title of the manuscript
- Enter the full names and institutional affiliations of ALL listed authors
- Enter ALL listed authors' institutional email addresses
- Identify the corresponding author
- Enter a running (abbreviated) title of no more than 45 characters (including spaces).
- Enter 3–6 keywords or phrases to assist in the selection of skilled reviewers in the field for the purposes of peer review.
- Provide an unstructured abstract of no more than 150 words
- Provide the names and email addresses of at least five potential preferred reviewers familiar with the field. Please make sure preferred reviewers are not from your university or institution or with whom you have collaborated. Anyone whom the author does not want to be considered should also be named as a non-preferred reviewer. Ultimate reviewer selection is at the Editor’s discretion.
- Confirm that the material has not been published or submitted for publication elsewhere.
It is incumbent upon the submitting author to ensure the accuracy and inclusion of all contributing authors' names and affiliations upon original submission of the manuscript. All authors' names must be entered into the Journal's submission site.
Note: There is a total limit of 200 MB per submission.
Create an Effective Title
- Manuscript titles should be brief, contain key terms, and clearly identify the purpose of the work conducted
- Manuscript titles should not exceed 15 -18 words. Exceptions can be made with the Editor’s approval
- Manuscript titles should be direct and to the point. Remember that the journal has a global readership, so clear and concise non-vernacular language is most effective
- Avoid the use of specific locations in the title
- Do not use proprietary/trademarked names in the title
- Do not use acronyms in the title unless they are universally recognized and accepted
- NOTE: The title page of your submission must be included as part of your main text document (not as a separate file).
All file names should be in English and contain only alphanumeric characters. Do not include spaces, symbols, special characters, dashes, dots, or underscores. Label each file with the first author's last name, followed by the content of the file (i.e.: SmithText; SmithTables; SmithFigureLegends; SmithFig1, etc.)
Important: Please upload individual files of all manuscript material as described herein — please do NOT upload a combined PDF file containing all material in your submission.
Preparation of Manuscript
Prepare text of manuscripts, figure legends, and tables in Microsoft Word, double spaced. The order of elements in each manuscript should be:
- Title page (with full manuscript title, all contributing authors’ full names, complete affiliations, mailing address, and telephone and e-mail address, a short running title, a denotation of the corresponding author and their complete contact information including address and email address, and a list of 3-6 keywords)
- Main text (do not embed figures or tables)
- Conclusion (as a separate paragraph, not as part of the Discussion section)
- Acknowledgments (if applicable)
- Authorship confirmation statement (see below)
- Author(s’) disclosure statement(s) (see below)
- Funding statement (see below)
- Figure legends
- Supplemental files (if applicable; supplied in Word, not as a PDF)
- Appendices (if applicable)
- Supplemental Information (if applicable); NOTE: Supplemental Information will not be copyedited or typeset; it will be posted online as supplied.)
The Authorship Confirmation Statement should detail each listed authors' contributions to and responsibilities for the manuscript. This text should also contain a statement that all co-authors have reviewed and approved of the manuscript prior to submission. Lastly, include a confirmation statement that the manuscript has been submitted solely to this journal and is not published, in press, or submitted elsewhere (posting on a non-peer-reviewed preprint server does not constitute prior publication).
- The abstract must be included in the main text file and placed on a separate page after the title page
- The abstract should be unstructured (background, materials and methods, results, and conclusions sections are not needed)
- The abstract should briefly summarize the background and rationale of the study, and clearly summarize the results and conclusions of the work
- The abstract should be no more than 150 words
- References are not permitted in the abstract
- Do not use proprietary or trade names in the abstract
Maximum word count for original articles should not exceed 3,000 words. In general, the text should be organized under the headings: Introduction, Materials and Methods, Results, Discussion, and Conclusions. Use only standard abbreviations, which can be found in the AMA’s Manual of Style for Authors & Editors or the Council of Biology Editors Style Manual, 10/e. At first usage, spell out terms and provide abbreviations in parentheses. Thereafter, use only the abbreviations. It is not necessary to spell out standard units of measure. Use generic names for drugs if possible. If you wish to use a proprietary drug name the first time it appears, use the generic name followed by the proprietary name, manufacturer, and location in parentheses.
References must be prepared in Word, double spaced, and numbered consecutively as they are cited in the text (using superscript numbers without parentheses). Include the reference section as part of the main text file, not as a separate file. References appearing for the first time in tables and figures must be numbered in sequence with those cited in the text where the table or figure is mentioned. Use journal abbreviations as provided by PubMed/Medline. If more than three authors are listed on an article, list the first three authors then use et al. (not italic) after the third author's name. If references to personal communications or unpublished data are used, they are not to be in the list of references. They should be referred to in the text in parentheses: (AB Jones, personal communication, date). Include among the references any articles that have been accepted but have not yet published; identify the name of publication and add "In Press." If the reference has been published online, provide the DOI number in place of the page range.
Sample style for references:
The CRISPR Journal requires DOIs for journal article references (see sample below), after the page range.
LaManna CM, Barrangou R. Enabling the rise of a CRISPR world. CRISPR J 2018;1:205–208. DOI: 10.1089/crispr.2018.0022.
Watson JD, Berry A, Davies K. DNA: The Story of the Genetic Revolution. New York, NY: Alfred A. Knopf, 2017.
Chapter in a book:
Hawkins JS. Targeted transcriptional repression in bacteria using CRISPR interference (CRISPRi). In: Lundgren M, Charpentier E, Fineran PC, eds. CRISPR: Methods and Protocols. New York, NY: Springer, 2015; pp. 349–362.
Website - please follow this structure for website references, including capitalization and punctuation:
Broad Institute. CRISPR Timeline. Available at https://www.broadinstitute.org/what-broad/areas-focus/project-spotlight/crispr-timeline Last accessed July 6, 2020.
Conference Proceedings - please follow this structure for Conference Proceedings, including capitalization and punctuation:
List all Authors' (or) Editors' names (last name first, followed by first and middle initials). Conference title. Date of conference. Location of conference. City of publisher: Publisher; Year of publication. Complete number of pages in proceedings book.
Preprints may be cited in same manner as a journal article; discretion is recommended as preprints are by definition not peer reviewed.
Figure legends should be uploaded as a separate Word file and double spaced. In the legend, provide explanations for any abbreviations, arrows, etc. that appear in the figure. If the figure is taken from a copyrighted publication, permission must be secured, appropriate credit must be given in the legend, and a corresponding reference must appear in the reference section.
All tables should be prepared in one single Word file. Provide a title for each table. Cite tables in sequence in the text. Explain abbreviations used in the body of the table in footnotes. All other types of table footnotes should be designated using superscript letters, not symbols. Do not repeat information that is given in the text, and do not make a table for data that can be given in the text in one or two sentences. If the table is taken from a copyrighted publication, permission must be secured, appropriate credit must be given in the legend, and a corresponding reference must appear in the reference section.
- Submission of high resolution .TIFF or .EPS figure files is strongly recommended.
- Figures should not be embedded within the manuscript file.
- Cite figures consecutively in text within parentheses.
- A legend should be supplied for each figure and all legends numbered consecutively.
- Images should not show the name of a patient or a manufacturer.
- Do not include any illustrations as part of your text file.
When appropriate, we encourage the judicious use of online-only supplementary information (SI). All information/data in the SI should be referred to in the article text, including reference to specific tables and figures in the SI. Upload supplementary tables, figures, and legends as separate files, either as "supplementary file" or "supplementary file for review only." The manuscript should be written so that the article which appears in the printed journal contains all data which are key to the conclusions and important for the reader to have direct access to when reading the article. Other supporting data and text are appropriate for the supplementary section.
The CRISPR Journal recommends depositing supporting plasmids and reagents to Addgene (www.addgene.org). For further information, please see the Perspective entitled, Enabling the Rise of a CRISPR World, by Caroline M. LaManna and Rodolphe Barrangou, published in The CRISPR Journal, 2018;1:205–208; DOI: 10.1089/crispr.2018.0022.
Following the references, provide the name and complete affiliation and institutional email address of the person to whom correspondence should be sent.
To upload a revision of a manuscript, the submitting author should log in to their Author Center and click on “Revised Manuscripts in Draft.” All revised submissions will be required to meet all formatting conditions described herein. Submissions that do not satisfy these requirements will be un-submitted and returned to the submitting author for proper configuration. Do NOT create a new submission for revisions of already-submitted manuscripts. Detailed instructions for submitting revised manuscripts are provided in an email which is sent to the corresponding author along with the reviewers' comments. Revised submissions routinely will undergo further review by the same reviewers who assessed the original submission, members of the editorial board, and/or the editor(s). Contact the Editorial Office immediately if the deadline for your revised submission has expired. Please note that an invitation to revise any submission does not guarantee acceptance.
Letters to the Editor
The CRISPR Journal will consider Letters to the Editor commenting on the scientific content of an article published in the Journal. Letters should not exceed 500 words of text and 5 references. Letters submitted for publication must be original and must not be submitted to any other publication simultaneously.
Journal Policies on:
Licensing Information: OPEN ACCESS and Copyright
Data Sharing and Preprint Policies
Post-Acceptance and Post-Publication Policies
Correction Statements / Retractions
Reprints, Permissions, & Social Media Use
Plagiarism Detection Software
Definitions of Scientific Misconduct
Responding to Allegations of Scientific Misconduct
Press Embargo Policy
Archiving and Preservation
For questions regarding manuscript submissions, contact our Author Services Division.
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Publishing in Subscription Journals
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Publishing Open Access
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