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Brought to you by Horizon Discovery, the leader in CRISPR functional genomics offering a large portfolio of CRISPR screening tools, reagents, and cell line generation.

 
PODCASTS
CRISPR Functional Genomics Miniseries

Episode #1:  Alejandro Chavez

In this episode, physician-scientist Alejandro Chavez (Columbia University) discusses the development and features of the CRISPR activation platform, which is commercially available from Horizon. Chavez also offers his views on the breadth of applications of CRISPRa/CRISPRi technology for genetics research.

Episode #2:  Cristina Ghirelli

In this podcast, Cristina Gherelli (Team Leader in Immuno Oncology R&D at Horizon Discovery) shares some of the latest tips in screening immune cells, particularly using pooled lentiviral T-cell screens. She also discussed the implications of this new screening application for immuno-oncology and autoimmunity research.

Episode #3:  Stanley Qi

Stanley Qi, Assistant Professor at Stanford University and Associate Editor with The CRISPR Journal, discusses the development and application of CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) in better understanding gene regulation and pathway relationships.

Episode #4: Omar Abuddayeh and Jonathan Gootenberg

Omar Abuddayeh and Jonathan Gootenberg (McGovern Institute for Brain Research, MIT) offer tips and strategies for minimizing off-target effects using CRISPR-Cas9. We also hear about their exciting work on SHERLOCK and CRISPR diagnostics, one of the highlights of their tenure in the Feng Zhang lab; and get a preview of some new directions now they are independent investigators.

 
WEBINARS

CRISPR Screening: From target selection to patient stratification

Original Air Date: May 14, 2019

In this webinar, Eric Shifrut, postdoctoral fellow at UCSF, and Benedict Cross, Head of Functional Genomic Screening at Horizon, will present the principles, strategies and experimental outcomes of CRISPR screening, including screening in primary T cells.

Genetic Rocket Fuel: The Landscape of CRISPR Technologies

Original Air Date: September 18, 2019

In this webinar, Dr. Ross Wilson, an alumnus of the Doudna laboratory at UC Berkeley, will discuss this remarkable array of molecular machines, the tools in an expanding toolkit that allows researchers to explore the ever-expanding territory.

 
ROUNDTABLES

Best Practices and Challenges in CRISPR Screening

The remarkable power of CRISPR technology is revolutionizing many areas of molecular biology, but none more so than functional genomics and high-throughput screening. In this engaging roundtable discussion, four distinguished experts in CRISPR technology development and application (Traver Hart, PhD, Martin Kampmann, PhD, Shondra Pruett-Miller, PhD, and Ophir Shalem, PhD) consider some of the best practices and challenges in performing successful CRISPR screens in a wide variety of experimental contexts.